Clobetasol-Topinate 30gm-Clobetasol Propionate

Clobetasol-Topinate 30gm-Clobetasol Propionate

Clobetasol Propionate

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Quantity Stength Unit Price Price Cart
1 Tube/s Clobetasol Propionate $3.00 $3.00
3 Tube/s Clobetasol Propionate $2.67 $8.01
6 Tube/s Clobetasol Propionate $2.50 $15.00


Brief description of Topinate:

This medication is used in adults to treat a variety of skin conditions (such as eczema, dermatitis, psoriasis). Clobetasol is the active ingredient which reduces the swelling, itching and redness that can occur in these types of conditions. This medication is a very strong (super-high-potency) corticosteroid.

How Topinate cream works?

The precise mechanism of the antiinflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Initially, however, clobetasol, like other corticosteroids, bind to the glucocorticoid receptor, which complexes, enteres the cell nucleus and modifies genetic transcription (transrepression/transactivation).

How to use Topinate cream?

Wash and dry your hands before applying. Clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2 times daily or as directed by your doctor. Do not bandage, wrap or cover the area unless directed to do so by your doctor. After applying the medication, wash your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma. Also, avoid getting the medication in your nose or mouth. If you get the medication in your eyes, nose, or mouth, rinse with plenty of water. Do not apply more than 50 grams (50 milliliters or 1.75 ounces) in a given week unless directed by your doctor.

Side-effects of using Topinate cream:

Burning, stinging, itching, irritation, dryness, or redness may occur when this medication is first applied to the skin.

Contraindications of using Topinate:

It may not be recommended to consume Topinate Cream if you have the following diseases, medical or physical conditions:

  • Decreased function of the adrenal gland
  • Diabetes

Drug-Interactions of using Topinate Cream:

Medicine and salt interactions may increase or decrease the activity of Topinate Cream when taken together with certain other medicines. Topinate Cream may interact with the following medicines and salts:

  • Cyclosporine
  • Prednisone

Precautionary Measures:

  • Clean the skin before a fresh dressing

Do not use in conditions such as fungal skin infections, severe flushing of skin on and around your nose, spotty red rash around your mouth, infected skin, itchy skin around the genitals

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